Cardio-Oncology in Brazil

Cardio-oncology for the 21st century: introduction.

Cardio-oncology: it takes two to translate.

As an emerging discipline focused on the cardiovascular care of cancer patients, cardio-oncology represents a novel platform for translational investigations. Toxic effects on the heart and vasculature caused by targeted cancer therapies can reveal insights into the biology of cardiovascular disease in humans. This phenomenon was first observed with trastuzumab, a monoclonal antibody that targe...

Cardio-Oncology: mechanisms of cardiovascular toxicity

The therapeutic options available to treat a wide range of malignancies are rapidly increasing. At the same time, the population being treated is aging with more cardiovascular risk factors, comorbid conditions, and associated poor cardiac reserve. Both traditional chemotherapeutic agents (for example, anthracyclines) and newer therapies (for example, targeted tyrosine kinase inhibitors and imm...

Cardio-oncology: a new medical issue

Due to the increasing number of long-term cancer survivors, the ageing of the population, as well as the increased incidence and prevalence of oncologic and cardiovascular diseases, the number of patients presenting oncologic and cardiologic co-morbidities are increasing. Accordingly, there is a rapidly growing need for a comprehensive and proficient management of patients in whom the two co-mo...

Pediatric hematology oncology in Brazil.

Brazil is the largest andmost populous country in SouthAmerica with an area of 8,511,965 km and a population of 170,029,560 habitants. It is composed mostly of young people; 2007 estimate reveals that 38% of the population is under 19 years of age [1]. For 2009, the Instituto Nacional de Câncer (National Cancer Institute) estimates around 9,890 patients with cancer under 19 years of age. There ...